Hmm...
For a start, what kind of plants are you keeping? Certain plants do have spots on their leaves. And what are the conditions they are kept? Fertilization?
If it's Java Ferns, it could be sprouting new leaves. If it's Anubias spp., then it could well be spot algae.
It's hard to give you constructive comments without you offering some information up front. Help us to help you.
Cheers,
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