Metronidazole is usually an good medication for treatment for several protozoan and anaerobic bacterial diseases (e.g Cryptocaryon, Hexamita {hole in head disease}, Ichthyophthirius). This medication does not affect the filtration media and can be easily removed with carbon when the treatment is over.
Usually, loaches will be the more sensitive species when it comes to medication as they are scaleless fauna. As such, medicating the tank with Cardinal Tetras should not be an issue at all. What exactly are you treating the loaches for?
Good luck with the treatment!
Cheers,
I have dwarf cichlids in my tanks! Do you?
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